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ask_variant_context

THE headline query. Given a CanFam4 position (e.g. '5:56189113'), return the variant's global + popmax frequency, breed-stratified cross-breed frequencies, ESM2/Pangolin/phyloP pathogenicity, gene context, linked diseases (v1.1), provenance, and deep links — in one call. Pass breed_context to also get that breed's AF + rank. cross_breed_full=True returns all 188 breeds (default: top_n).

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
top_nNo
positionYes
breed_contextNo
cross_breed_fullNo

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault

No arguments

TDQS

A4.6/5.0
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

No annotations are provided, so the description carries full burden. It discloses the tool returns many data types, explains optional breed_context and cross_breed_full behaviors, and notes the default for top_n. It does not mention potential performance considerations or rate limits, but is otherwise transparent.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is a single, dense sentence that front-loads key information and packs in all details without wasted words. Every phrase adds value.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the output schema exists, the description does not need to detail return values. It covers all tool capabilities and parameter behaviors, making it complete for a complex tool with four parameters.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters5/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

With 0% schema description coverage, the description fully compensates by explaining all four parameters: position format, breed_context string behavior, cross_breed_full boolean effect (all 188 breeds vs top_n), and top_n default (5). This adds significant meaning beyond the bare schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the tool returns comprehensive variant data for a CanFam4 position, listing all included fields (frequency, pathogenicity, gene context, diseases, provenance, deep links). It distinguishes from siblings by being the 'headline query' that bundles multiple data types in one call.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description implies this tool is for comprehensive variant context, but does not explicitly state when to use alternatives like variant_lookup or breed_variant_frequency. However, the context of sibling tools and the phrase 'headline query' provide clear usage direction.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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TDQS

A3.6/5.0
Disambiguation4/5

Tools are mostly distinct with clear purposes, but some overlap exists between disease-related tools (disease_lookup vs disease_links) and between ask and ask_the_graph. Descriptions help differentiate, but an agent might still misselect.

Naming Consistency2/5

Naming patterns are inconsistent: some tools use verb_noun (ask, search_diseases), others use noun_noun (breed_similarity, disease_bridge), and some use descriptive phrases. No consistent convention observed.

Tool Count5/5

18 tools is well-scoped for a canine genetics knowledge base. Each tool serves a distinct function covering breed, disease, variant, and query capabilities without being overwhelming.

Completeness5/5

The tool set covers all major aspects of the domain: breed profiles, disease lookup with links, variant querying, semantic search, and metadata. No obvious gaps for the stated educational purpose.