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Search Ligands

search_ligands
Read-onlyIdempotent

Search the Guide to PHARMACOLOGY (IUPHAR/BPS) — an expert-curated pharmacology database — for drug ligands by name. Returns matching ligands with their GtoPdb ligand id, type (e.g. Synthetic organic, Peptide, Antibody, Metabolite), and approval status. Use the returned ligand id with ligand_interactions to find which protein targets it acts on. Requires a GtoPdb API key — register free at guidetopharmacology.org/login.jsp and pass your own via _apiKey. Complements ChEMBL/DrugBank.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
nameYesLigand name or fragment to search for, e.g. "aspirin" or "imatinib".
limitNoMax results to return (default 15).

Schema Changelog

Changes observed during successful MCP inspections.

  1. Changed1 schema field changed
    • changedInput schema / examples
      Previous value: -[
      -  {
      -    "name": "aspirin"
      -  },
      -  {
      -    "limit": 10,
      -    "name": "imatinib"
      -  }
      -]New value: +[
      +  {
      +    "_apiKey": "your-guidetopharmacology-api-key",
      +    "name": "aspirin"
      +  },
      +  {
      +    "_apiKey": "your-guidetopharmacology-api-key",
      +    "limit": 10,
      +    "name": "imatinib"
      +  }
      +]
  2. Changed1 schema field changed
    • addedInput schema / examples
      Added value: +[
      +  {
      +    "name": "aspirin"
      +  },
      +  {
      +    "limit": 10,
      +    "name": "imatinib"
      +  }
      +]
  3. First observed

TDQS

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