| edge | No | ProtScale relative weight of the window's edge residues, 0-1 (default 1 = unweighted). | |
| kind | No | which profile to compute. Ignore this and pass `scaleId` to reach the full ProtScale catalogue. | hydropathy |
| scale | No | hydropathy scale. Values: KyteDoolitle (Kyte & Doolittle (1982)), Aboderin (Aboderin (Int J Biochem 2:537)), AbrahamLeo (Abraham & Leo (1987)), Argos (Argos (Eur J Biochem 128:565)), BlackMould (Black & Mould (1991)), BullBreese (Bull & Breese (1974)), Casari (Casari & Sippl, hydrophobic potential (JMB 224:725)), Cid (Cid (Protein Eng 5:373)), Cowan3.4 (Cowan at pH 3.4 (1990)), Cowan7.5 (Cowan at pH 7.5 (1990)), Eisenberg (Eisenberg, normalized consensus (1984)), Engelman (Engelman, transfer free energy (Annu Rev Biophys 15:321)), Fasman (Fasman (1989)), Fauchere (Fauchere (1983)), GoldSack (Goldsack & Chalifoux, free energy of mixing (J Theor Biol 39:645)), Guy (Guy, transfer free energy kcal/mol (1985)), Jones (Jones (J Theor Biol 50:167)), Juretic (Juretic (Theor Comput Chem 5:405)), Kidera (Kidera factors (J Protein Chem 4:23)), Miyazawa (Miyazawa, contact energy from 3D structures (1985)), Parker (Parker, HYDROPHILICITY from HPLC retention (1986)), Ponnuswamy (Ponnuswamy, folded-protein character (Prog Biophys Mol Biol 59:57)), Rose (Rose (1985)), Roseman (Roseman (1988)), Sweet (Sweet, optimized matching OMH (1983)), Tanford (Tanford (1962)), Wilson (Wilson, hydrophobic constants from HPLC retention (1981)), Zimmerman (Zimmerman (J Theor Biol 21:170)). Only applies when kind is hydropathy. | KyteDoolitle |
| _files | No | The project: record references shaped like _subject. Their records become library documents a tool names in sequences/parts/document; a trace or alignment is found by file name. | |
| window | No | ProtScale window in residues, odd (default 9). IGNORED for 'flexibility', whose Vihinen parameters are only defined at 9. Only applies when kind is hydropathy or hydrophilicity or accessibility or interior. | |
| protein | Yes | the protein sequence (unambiguous one-letter codes); wire it from translate_sequence. | |
| scaleId | No | any of the 57 ExPASy ProtScale scales, or the 14 Biopython tables ProtScale does not publish. Pass this INSTEAD of `kind` and `scale`, never alongside them: sending `scaleId` together with `kind` is refused by name rather than one silently winning. The panel opens on `scaleId: hydropath-doolittle`, which computes the same curve as the `kind`/`scale` defaults. Values: molecularweight (Molecular weight), numbercodons (Number of codon(s)), bulkiness (Bulkiness), polarityzimmerman (Polarity / Zimmerman), polaritygrantham (Polarity / Grantham), refractivity (Refractivity), recognitionfactors (Recognition factors), hphob-eisenberg (Hphob. / Eisenberg et al.), hphob-sweet (Hphob. OMH / Sweet et al.), hphob-woods (Hphob. / Hopp & Woods), hydropath-doolittle (Hydropath. / Kyte & Doolittle), hphob-manavalan (Hphob. / Manavalan et al.), hphob-leo (Hphob. / Abraham & Leo), hphob-black (Hphob. / Black), hphob-breese (Hphob. / Bull & Breese), hphob-fauchere (Hphob. / Fauchere et al.), hphob-guy (Hphob. / Guy), hphob-janin (Hphob. / Janin), hphob-miyazawa (Hphob. / Miyazawa et al.), hphob-argos (Hphob. / Rao & Argos), hphob-roseman (Hphob. / Roseman), hphob-tanford (Hphob. / Tanford), hphob-wolfenden (Hphob. / Wolfenden et al.), hphob-welling (Hphob. / Welling & al), hphob-wilson (Hphob. HPLC / Wilson & al), hphob-parker (Hphob. HPLC / Parker & al), hphob-ph3-4 (Hphob. HPLC pH3.4 / Cowan), hphob-ph7-5 (Hphob. HPLC pH7.5 / Cowan), hphob-mobility (Hphob. / Rf mobility), hplchfba (HPLC / HFBA retention), hplctfa (HPLC / TFA retention), transmembranetendency (Transmembrane tendency), hplc2-1 (HPLC / retention pH 2.1), hplc7-4 (HPLC / retention pH 7.4), buriedresidues (% buried residues), accessibleresidues (% accessible residues), hphob-chothia (Hphob. / Chothia), hphob-rose (Hphob. / Rose & al), ratioside (Ratio hetero end/side), averageburied (Average area buried), averageflexibility (Average flexibility), alpha-helixfasman (alpha-helix / Chou & Fasman), beta-sheetfasman (beta-sheet / Chou & Fasman), beta-turnfasman (beta-turn / Chou & Fasman), alpha-helixroux (alpha-helix / Deleage & Roux), beta-sheetroux (beta-sheet / Deleage & Roux), beta-turnroux (beta-turn / Deleage & Roux), coilroux (Coil / Deleage & Roux), alpha-helixlevitt (alpha-helix / Levitt), beta-sheetlevitt (beta-sheet / Levitt), beta-turnlevitt (beta-turn / Levitt), totalbeta-strand (Total beta-strand), antiparallelbeta-strand (Antiparallel beta-strand), parallelbeta-strand (Parallel beta-strand), a-a-composition (A.A. composition), a-a-swiss-prot (A.A. comp. in Swiss-Prot), relativemutability (Relative mutability), biopython-argos (Argos), biopython-casari (Casari & Sippl), biopython-cid (Cid et al.), biopython-engelman (Engelman (GES)), biopython-fasman (Fasman), biopython-goldsack (Gold Sack & Chalifoux), biopython-jones (Jones), biopython-juretic (Juretic et al.), biopython-kidera (Kidera et al.), biopython-ponnuswamy (Ponnuswamy), biopython-zimmerman (Zimmerman (hydrophobicity)), biopython-flex (Flexibility (Vihinen)), biopython-surface-accessibility (Surface accessibility (Emini)), biopython-janin (Janin (Biopython rounding)). | |
| _subject | No | The record to act on: exactly one of sequence, accession (+source), sample (an id from list_samples) or file ({name, text} or {name, base64}); record_index picks one record of several. | |
| normalize | No | ProtScale's 'normalize the scale from 0 to 1' — rescales the twenty scale values before windowing, so profiles from different scales are comparable. Requires `scaleId`. | |
| weightVariation | No | ProtScale's weight model between the centre and the edge weight: 'linear' steps down evenly, 'exponential' decays steeply near the centre. Requires `scaleId`; identical at edge 1. | linear |