antibody_isotype
Read-only
Name the CONSTANT region of an antibody chain: which immunoglobulin gene and allele it carries (IGHG1, IGHA2, IGKC, IGLC2 …), and where each IMGT domain sits on it — CH1, the hinge, CH2, CH3, the secretory tail and the membrane exons, or the single C region of a light chain. A domain search says 'a C1-set immunoglobulin domain'; this says which isotype it is. Reads IMGT/GENE-DB's own per-label translations for every species, and is graded against UniProtKB's curated human constant chains and their CH1/hinge/CH2/CH3 regions.
Input Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| _files | No | The project: record references shaped like _subject. Their records become library documents a tool names in sequences/parts/document; a trace or alignment is found by file name. | |
| protein | Yes | the chain (one-letter amino acids); the constant region in it is found, so a whole heavy chain is fine. | |
| species | No | only consider genes of this species, spelled as IMGT spells it (Homo sapiens, Mus musculus). Left out, every species in the catalogue competes and the answer says which won. | |
| _subject | No | The record to act on: exactly one of sequence, accession (+source), sample (an id from list_samples) or file ({name, text} or {name, base64}); record_index picks one record of several. | |
| minIdentity | No | a domain matching less of its reference than this is not reported. |
Output Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| gene | Yes | the IMGT gene the constant region matches (IGHG1) | |
| allele | Yes | the allele, as IMGT numbers them (01) | |
| domains | Yes | each IMGT label placed on the chain: label, start, end (1-based inclusive), identity, coverage | |
| species | Yes | the species whose gene answered | |
| identity | Yes | identical residues over every aligned column, 0 to 1 |