| section | Yes | Which methodology section to fetch. 'rnpv' covers the core risk-adjusted NPV calculation: cumulative PoS, midpoint-discounted risk-adjusted development costs, the S-curve ramp/plateau/LOE revenue lifecycle net of COGS/SG&A/tax, WACC discounting, the rNPV and Unadjusted-NPV equations, Monte Carlo / expected NPV, and one-at-a-time sensitivity; 'backtest' covers the validation methodology and AUC/CI numbers; 'pos-calibration' covers the indication × modality × biomarker matrix, expanded modality normalization into the eight benchmark baselines, the scored multipliers including the engine 2.6.0 biomarker_quality drug-specific multiplier (oncology solid tumor, Phase II/III), the Phase 1 ORR extracted-but-not-scored signal with its Phase 0 governance disclosure, and the non-scored drug-specific risk flags; 'ira-framework' covers the Year-9/Year-13 MFP cliff modeling and the separate IRA classification for expanded modalities such as RNA Therapeutics, Protein Degrader, Radioligand, Oncolytic Virus, and Cancer Vaccine; 'development-paths' covers development-path tiers, automatic-effect policy, and the no path-based PoS/default-multiplier rule; 'stage-normalization' covers exact clinical labels, work packages, canonical PoS gates, and the no label-only PoS modifier rule for Phase 1b/2a/2b, adaptive, pivotal, expansion, platform, bridging, and related labels; 'evidence-standards' covers source tiers and freshness rules; 'network-benchmarks' covers anonymization and cohort cuts; 'cogs-benchmark' covers the per-modality COGS% default bands and price-sensitivity methodology; 'sga-benchmark' covers the per-commercial-model SG&A% default bands (orphan/specialty/primary-care); 'tax-benchmark' covers the US-statutory-21% default tax rate, effective-rate reality, and the NOL cap; 'sec-deal-terms' covers the SEC EDGAR 8-K Item 1.01 deal-term extraction pipeline (cohort, extractor + classifier versions, fields extracted, v0 vs v1 scope). | |