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The Cure Protocol

get_trial_related_research

Read-only

USE WHEN you have a trial (canonicalId from search_world_trials) and need the PUBLISHED RESEARCH around it, or when you want to find related registrations in registries this index does not ingest. Returns three separately-labelled layers: (1) registryDeclared — publications the registry record itself declares, with kind=results/background/derived/protocol, the strongest available evidence that a trial reported; (2) literature — Europe PMC records whose indexed text or accession list mentions one of the trial’s registration identifiers, with journal, year, DOI/PMID, open-access flag and citation count; (3) crossRegistryMentions — OTHER registry identifiers (ANZCTR, ChiCTR, JPRN, DRKS, CTRI, CTIS and more) found in the title/abstract of that literature, each flagged inIndex true/false. THIS IS A SIDECAR: nothing it returns is in the trial index or in any count, and an identifier with inIndex=false is a literature mention only — never report it as a trial this index holds. NEXT: get_world_trial for the canonical record, find_trial_registrations to check for double-counting.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
limitNoMaximum literature hits per identifier searched.
includeNoComma-separated sections: declared, literature, crossref. Default all three.
canonicalIdYesCanonical trial id, e.g. NCT04333823 or ISRCTN50189673.

Schema Changelog

Changes observed during successful MCP inspections.

  1. First observed

TDQS

A4.8/5.0
Behavior5/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Goes well beyond readOnlyHint/openWorldHint: it declares itself a SIDECAR whose results appear in no count, describes the provenance and evidence strength of each layer (registryDeclared kind=results is 'the strongest available evidence'), and warns that inIndex=false identifiers must never be reported as trials this index holds. That is exactly the kind of behavioral constraint annotations cannot express. Minor tension: the tool reaches into Europe PMC and other registries while openWorldHint=false, which is defensible for a fixed external API but worth noting.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Dense but front-loaded: usage condition first, then the three return layers, then the SIDECAR caveat and next steps. The numbered layer list is scannable and every sentence carries information, though the single long paragraph could be broken up for faster parsing.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

No output schema exists, so the description carries the full return-value burden and does so: it names all three layers, the fields inside them (kind, journal, year, DOI/PMID, open-access flag, citation count, inIndex), and the interpretation rule for the ambiguous case. An agent has everything needed to call it and to interpret the response correctly.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters4/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema coverage is 100%, so the baseline is 3. The description nevertheless adds meaning for 'include' by naming the three layers (declared, literature, crossref) that correspond to the comma-separated section values, and clarifies the semantic distinction between density/limit context and identifier mentions. Limit's exact semantics remain in the schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

States a specific verb and resource (retrieve published research around a trial) and explicitly distinguishes itself from siblings by naming search_world_trials as the id source, get_world_trial for the canonical record, and find_trial_registrations for double-counting. The three output layers are enumerated, so the agent knows exactly what it produces.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines5/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

Opens with an explicit 'USE WHEN' clause giving the prerequisite (a trial canonicalId) and two distinct motivations (published research around a trial; related registrations not ingested by this index). A 'NEXT' clause routes to the correct alternative tools, covering when-not-to-rely-on-this.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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