nullary

search_pathogen_history

Read-onlyIdempotent

Vaccine + antimicrobial + antibody failures for a pathogen.

Tool call template

Replace each placeholder with a value matching the input schema. Only required parameters are included; add optional parameters as needed.

{
  "id": 1,
  "jsonrpc": "2.0",
  "method": "tools/call",
  "params": {
    "arguments": {
      "pathogen": "<pathogen>"
    },
    "name": "search_pathogen_history"
  }
}

Input Schema

Name	Required	Description	Default
`tier`	No	Confidence tier. 'curated' (default) returns the credible layer; 'all' also includes high-volume screening-grade rows (PubChem HTS inactives, CRISPR non-essential tails).	curated
`limit`	No	Maximum number of findings to return (1–100, default 25).
`offset`	No	Number of findings to skip before this page, for pagination (default 0).
`pathogen`	Yes	pathogen name (required)

Output Schema

Name	Required	Description
`findings`	No	Matching negative findings (same shape as the REST /findings endpoint).
`has_more`	No	True when more results exist beyond this page.
`coverage_note`	No	Honest coverage caveat for thin Phase-1 modalities (present only when relevant).
`query_metadata`	Yes	Echo of the resolved query — tool, limit, offset, and any applied presets.
`returned_count`	No	Findings returned in this page.

Schema Changelog

Changes observed during successful MCP inspections.

Changed3 schema fields changedMay 25, 2026

addedInput schema / properties / limit / description

Added value: +"Maximum number of findings to return (1–100, default 25)."

addedInput schema / properties / offset / description

Added value: +"Number of findings to skip before this page, for pagination (default 0)."

changedOutput schema / (root)

Previous value: -nullNew value: +{
+  "properties": {
+    "coverage_note": {
+      "description": "Honest coverage caveat for thin Phase-1 modalities (present only when relevant).",
+      "type": "string"
+    },
+    "findings": {
+      "description": "Matching negative findings (same shape as the REST /findings endpoint).",
+      "items": {
+        "type": "object"
+      },
+      "type": "array"
+    },
+    "has_more": {
+      "description": "True when more results exist beyond this page.",
+      "type": "boolean"
+    },
+    "query_metadata": {
+      "description": "Echo of the resolved query — tool, limit, offset, and any applied presets.",
+      "type": "object"
+    },
+    "returned_count": {
+      "description": "Findings returned in this page.",
+      "type": "integer"
+    }
+  },
+  "required": [
+    "query_metadata"
+  ],
+  "type": "object"
+}

First observedMay 25, 2026

TDQS

B3.4/5.0

Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint=true, destructiveHint=false, openWorldHint=true, and idempotentHint=true, so the safety profile is covered. The description adds the qualifier 'failures', indicating the tool returns negative outcomes only, which is not captured by annotations. However, it provides no additional behavioral context such as pagination behavior, result sorting, or the meaning of the curated vs. all tier.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is a single, succinct fragment of seven words that immediately conveys the tool's subject. It is front-loaded and contains no filler, though it is so terse that it borders on under-specification. It earns a 4 for efficiency rather than a 5 because it is not a complete sentence.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness3/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With a rich input schema, output schema, and comprehensive annotations, the description's minimalism is partially acceptable. It names the key result category (failures) and the pathogen focus, but it does not explain the curated vs. all tier behavior, which is a significant part of the tool's usage. Given the abundance of sibling tools, the description is adequate but not fully complete.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, with all four parameters (pathogen, tier, limit, offset) already fully described in the input schema. The description does not add any parameter-specific meaning beyond what the schema provides; the baseline of 3 applies because the schema carries the full semantic weight.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description 'Vaccine + antimicrobial + antibody failures for a pathogen' clearly specifies the tool's scope as a combination of three failure types for a given pathogen, which distinguishes it from siblings like search_failed_vaccines or search_target_history. However, it lacks an explicit verb such as 'search' or 'list', making it a noun phrase rather than a fully specified action.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description implies usage when a user needs failure data across vaccine, antimicrobial, and antibody categories for a pathogen, but it does not explicitly state when to prefer this tool over more specific alternatives like search_failed_vaccines or search_failed_clinical_antibodies. No exclusions or alternative tool names are provided.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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