"How to run a Python file using Claude Desktop" matching MCP tools:

• start_comfyuiA

  ComfyUI MCP

  Starts ComfyUI using saved process info from a prior stop, supporting Desktop and manual Python installs, and polls API until ready.

  MIT

• query_file_ownershipA

  arch-mcp

  Identify which Arch Linux package owns a file, list a package's files, or search for files across all installed packages using three query modes.

  GPL 3.0

• run_mutation_testsA

  io.github.phoenice-labs/universal-test-framework

  Run mutation testing on a source and test file pair. Returns coverage metrics with auto-detected adapters for Python, JavaScript, TypeScript, Java, and Go.

  MIT

• reanalyze_mediaA

  Speak AI MCP Server

  Re-run specific AI analyses on a media file using updated models, covering insights, sentiment, filler words, and embeddings.

  MIT

• globus_compute_register_python_functionA

  globus-mcp

  Register a Python function with Globus Compute to enable remote execution. Then submit tasks to run the function on compute endpoints.

  Apache 2.0

• text_file__read_sliceA

  text_file_read_and_refactor_mcp

  Read a specific slice of a text file using Python-style start, stop, step parameters. Automatically handles BOM and encoding for efficient content access.

  Apache 2.0

• execute_script_on_fileB

  Blender Copilot MCP Server

  Run Python scripts on .blend files in headless mode to perform batch modifications, with optional saving of the file.

  MIT

• rag_get_install_configC

  ragmap

  Retrieve ready-to-use installation configurations for MCP servers, formatted for Claude Desktop or generic hosts.

  MIT

• check_instrumentationA

  observe-instrument-mcp

  Audit a Python AI agent file to identify missing ioa-observe-sdk instrumentation and receive specific recommendations.

  Apache 2.0

• llm_codexA

  ypollak2/llm-router

  Send a task to Codex CLI to run non-interactively with OpenAI models, bypassing Claude quota limits.

  MIT

• estimate_costA

  codelore-mcp

  Estimate the number of Claude CLI calls required to ingest a code repository. Reports file counts per language and total subprocess calls to help assess scope before running the full ingestion.

  MIT

• transcribe_audioA

  macwhisper-mcp-server

  Transcribe a local audio file on your Mac to text using MacWhisper. Returns the transcript.

  MIT

• launch_on_headless_desktopA

  lowlevel-computer-use-mcp

  Run GUI applications on a hidden desktop for automated control without interfering with the visible desktop.

  MIT

• create_project_fullA

  Metis Public Health

  Create a new project with full Metis integration by adding a database record, generating CLAUDE.md, and optionally linking to Claude Desktop. Supports automatic description inference from folder contents.

  AGPL 3.0

• start_comfyuiA

  comfyui-mcp

  Restart ComfyUI using saved process info from a prior stop. Works for Desktop app and manual Python installs, with up to 60 seconds wait for API readiness.

  MIT

• restart_claudeA

  MCP Autostarter

  Restarts the Claude Desktop application specifically when the MCP Autostarter fails, ensuring uninterrupted workflow and plugin reloading without closing the app.

  MIT

• run_flowA

  metaflow-mcp-server

  Run a Metaflow workflow from a local Python file. Optionally set parameters, tags, and max workers for parallel execution.

  Apache 2.0

• generate_claude_desktop_configA

  aimarket-mcp-packager

  Generates a claude_desktop_config.json snippet to register a Docker-based MCP server with Claude Desktop.

  MIT

• switch_modelA

  whisper-windows-mcp

  Change the active Whisper model for the current session without restarting Claude Desktop. Provide a model filename or full path; the model must already be installed.

  Inno Setup

• everything_file_infoA

  @shxiaj/everything-mcp

  Retrieve Windows file attributes and run count for any file or folder path using Everything's indexing.

  MIT