GxP MDM MCP Server
Allows querying a Computerized System Inventory stored as a knowledge graph in Neo4j using Cypher, with tools for system inventory, system details, downstream blast radius, upstream lineage, regulations, interfaces, validation gaps, periodic reviews, high-risk functions, supplier risk, data lineage, and change impact assessment.
This server does not currently have a deployable release on Glama. Follow the repository's setup instructions to install and configure it for your MCP client, including any required credentials and local dependencies.
GxP MDM MCP Server - Cypher Tools for Claude / ChatGPT / Cursor
This MCP server exposes your Computerized System Inventory as a Knowledge Graph via Cypher queries. Any Claude/ChatGPT agent can now query GxP master data without hallucinating.
Architecture
Claude / ChatGPT / Cursor
|
| MCP (stdio)
v
mcp_server.py (14 tools)
|
| Cypher queries
v
Neo4j (or MOCK mode: NetworkX + JSON) <- your MDM golden recordWhy Cypher?
Blast radius is a graph traversal:
MATCH (start)-[:SENDS_VIA*1..3]->(downstream)— impossible in SQLData lineage for ALCOA+ investigations
Regulation ground truth — agent can only cite clauses returned by Cypher, prevents hallucination
Related MCP server: coderadius
14 Tools Exposed
Tool | Cypher | What it does |
| Custom | Safe read-only Cypher for exploration |
|
| Full inventory - auditors ask this first |
| Full subgraph | System + functions + e-records + supplier + interfaces |
|
| Killer app: What downstream GxP systems are impacted by change? |
| Reverse traversal | Where does data come from? |
|
| Anti-hallucination: only these clauses can be cited |
|
| API/file/manual interfaces with GxP flag |
|
| Non-validated GxP Direct systems |
|
| Overdue periodic reviews |
|
| E-sig, batch release, potency |
|
| Supplier audit status, SOC2 |
|
| Lineage for a record type |
|
| GxP Direct inventory |
| Composite | Orchestrates 3 Cypher queries + generates impact assessment per GAMP 5 / CSA |
Quick Start (No Neo4j needed - Mock Mode)
cd gxp_mdm_mcp_server
pip install -r requirements.txt
# Mock mode: uses JSON + NetworkX, no Neo4j required
python scripts/test_tools.py
# Should show:
# - List 4 systems
# - Veeva QMS details with downstream SAP
# - Blast radius: Veeva -> SAP
# - REJECT for audit trail purge
# - Minor for version upgradeMock mode is perfect for POC and Claude Desktop testing.
Prod Mode with Neo4j
# .env - set Neo4j creds
cp .env.example .env
# Edit .env with your Neo4j URI
# Start Neo4j
docker-compose up -d neo4j
# Load sample data + schema
python scripts/load_sample_data.py
# Test with Neo4j
python scripts/test_tools.py
# Start API harness (optional)
uvicorn src.api_server:app --reload --port 8000
# http://localhost:8000/cypher/list_all_systems
# http://localhost:8000/cypher/blast_radius?system_id=SYS-VEEVA-QMS-001Claude Desktop Config
Find your Claude config:
~/Library/Application Support/Claude/claude_desktop_config.json(Mac) or%APPDATA%/Claude/claude_desktop_config.json(Win)Add (use absolute path):
{
"mcpServers": {
"gxp-mdm-cypher": {
"command": "python",
"args": ["/absolute/path/to/gxp_mdm_mcp_server/src/mcp_server.py"],
"env": {
"NEO4J_URI": "",
"NEO4J_USERNAME": "neo4j",
"NEO4J_PASSWORD": "password"
}
}
}
}For mock mode, leave NEO4J_URI empty. For Neo4j, set to bolt://localhost:7687.
Restart Claude Desktop. You should see 14 tools under 🔌.
Try prompts:
List all GxP Direct systems in my inventory
> calls list_all_systems(gxp_impact="Direct")
What happens if I change Veeva QMS? Show blast radius
> calls get_blast_radius(system_id="SYS-VEEVA-QMS-001")
Assess this change: Enable audit trail purge after 7 years for Veeva QMS
> calls assess_change_impact -> should REJECT per 21CFR11.10(e)
Assess Veeva upgrade from 24R1 to 24R2 with no e-sig change
> calls assess_change_impact -> should be Minor per CSA low riskCursor Config
See config/cursor_config.json.example - add to .cursor/mcp.json
ChatGPT (with MCP support)
If using ChatGPT custom GPT with MCP, use config/chatgpt_mcp_config.json as reference. ChatGPT will call tools via stdio.
Cypher Queries - Ground Truth
All queries in src/cypher_tools.py. Key ones:
Blast radius (the moat):
MATCH (start:ComputerizedSystem {system_id: $system_id})
MATCH path = (start)-[:SENDS_VIA*1..$depth]->(downstream:ComputerizedSystem)
WHERE downstream.gxp_impact IN ['Direct', 'GxP Relevant']
RETURN downstream.system_id, length(path) as distanceRegulation anti-hallucination:
MATCH (s:ComputerizedSystem {system_id: $system_id})
OPTIONAL MATCH (s)-[:HAS_FUNCTION]->(f)-[:REGULATED_BY]->(reg)
RETURN collect(DISTINCT reg) as regulationsAgent must ONLY cite clause_ids returned here.
From POC to Production
Replace
data/*.jsonwith real Veeva Vault API + ServiceNow CMDB + OktaAdd write tools (with approval workflow) for updating validation_status
Add vector search tool for regulation RAG (embed GAMP 5 2nd Ed)
Add periodic review agent that calls
find_periodic_review_overdueon schedule
You now own the layer every CSV agent must query.
Troubleshooting
No module named mcp:pip install mcpClaude doesn't see tools: Check absolute path in config, restart Claude, check logs
~/Library/Logs/Claude/mcp*.logNeo4j connection fails: Falls back to mock mode automatically - check
NEO4J_URI
Good luck cornering the market.
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