BioMCP

Feature: Search Clinical Trials Scenario Outline: Search trials by condition Given I build a trial query with condition "<condition>" When I perform a trial search Then the response should contain a study with condition "<condition>" And the study should have a valid NCT ID Examples: | condition | | lung cancer | | melanoma | Scenario: Search trials with multiple filters Given I build a trial query with condition "melanoma" And I add intervention "BRAF" And I set recruiting status to "OPEN" And I set study type to "INTERVENTIONAL" When I perform a trial search Then the response should contain a study with condition "melanoma" And the study should include intervention "BRAF" And the study should have recruiting status "RECRUITING" And the study should be of type "INTERVENTIONAL" Scenario: Search trials by location Given I build a trial query with condition "breast cancer" And I set location to latitude "42.3601" longitude "-71.0589" within "100" miles When I perform a trial search Then the response should contain a study with condition "breast cancer" And at least one study location should be in "Massachusetts" Scenario: Search trials with field filtering Given I build a trial query with condition "diabetes" When I perform a trial search Then the response should contain a study with condition "diabetes" And the study should have required fields Scenario: Search trials by general terms Given I build a trial query with term "glioblastoma treatment" When I perform a trial search Then the response should contain a study with term "glioblastoma" And the study should have a valid NCT ID Scenario: Search trials by NCT ID Given I build a trial query with nct_id "NCT04179552" When I perform a trial search Then the response should contain a study with NCT ID "NCT04179552" Scenario: NCT ID intersection with condition filter Given I build a trial query with condition "melanoma" And I add nct_id "NCT07006480" When I perform a trial search Then the response should not contain a study with NCT ID "NCT07006480" Scenario: Search trials by phase Given I build a trial query with condition "leukemia" And I set phase to "PHASE3" When I perform a trial search Then the response should contain a study with condition "leukemia" And the study should be in phase "Phase 3" Scenario: Sort trial search results Given I build a trial query with condition "arthritis" And I set sort order to "LAST_UPDATE" When I perform a trial search Then the response should contain a study with condition "arthritis" And the studies should be sorted by "last_update_date" Scenario: Filter trials by age group Given I build a trial query with condition "alzheimer" And I set age group to "SENIOR" When I perform a trial search Then the response should contain a study with condition "alzheimer" And the study should include age group "Older Adult" Scenario: Filter trials by primary purpose Given I build a trial query with condition "diabetes" And I set primary purpose to "TREATMENT" When I perform a trial search Then the response should contain a study with condition "diabetes" And the study should have primary purpose "Treatment" Scenario: Filter trials by date range Given I build a trial query with condition "covid" And I set min date to "2020-01-01" And I set date field to "STUDY_START" When I perform a trial search Then the response should contain a study with condition "covid" And the study should have a start date after "2020-01-01" Scenario: Filter trials by intervention type Given I build a trial query with condition "cancer" And I set intervention type to "DRUG" When I perform a trial search Then the response should contain a study with condition "cancer" And the study should have intervention type "Drug" Scenario: Paginate trial search results Given I build a trial query with condition "hypertension" # In a real scenario, next_page_hash comes from previous search # For test, we'll skip setting it since it requires a valid format When I perform a trial search Then the response should contain studies Scenario: Search trials with prior therapy filter Given I build a trial query with condition "lung cancer" And I add prior therapy "osimertinib" When I perform a trial search Then the response should contain a study with condition "lung cancer" And the study eligibility should mention "osimertinib" with "prior" context Scenario: Search trials with progression on therapy filter Given I build a trial query with condition "melanoma" And I add progression on "vemurafenib" When I perform a trial search Then the response should contain a study with condition "melanoma" And the study eligibility should mention "vemurafenib" with "progression" context Scenario: Search trials with required mutations Given I build a trial query with condition "lung cancer" And I add required mutation "EGFR L858R" When I perform a trial search Then the response should contain a study with condition "lung cancer" And the study eligibility should mention "EGFR L858R" Scenario: Search trials with excluded mutations Given I build a trial query with condition "lung cancer" And I add excluded mutation "KRAS" When I perform a trial search Then the response should contain a study with condition "lung cancer" And the study eligibility should exclude "KRAS" Scenario: Search trials with biomarker expression Given I build a trial query with condition "lung cancer" And I add biomarker expression "PD-L1" with value "≥50%" When I perform a trial search Then the response should contain a study with condition "lung cancer" And the study eligibility should mention "PD-L1" with expression "≥50%" Scenario: Search trials by line of therapy Given I build a trial query with condition "breast cancer" And I set line of therapy to "2L" When I perform a trial search Then the response should contain a study with condition "breast cancer" And the study eligibility should mention "second line" therapy Scenario: Search trials excluding brain metastases Given I build a trial query with condition "lung cancer" And I set allow brain mets to "False" When I perform a trial search Then the response should contain a study with condition "lung cancer" And the study eligibility should exclude "brain metastases" Scenario: Search trials by lead sponsor Given I build a trial query with condition "cancer" And I add lead sponsor "National Cancer Institute" When I perform a trial search Then the response should contain a study with condition "cancer" And the study should have lead sponsor "National Cancer Institute"