Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?
Annotations already declare readOnly, idempotent and non-destructive, so the safety profile is covered; the description goes well beyond that by disclosing the matching cascade (exact alias, normalized alias, trigram, edit distance), the normalization rules, the 2-error edit-distance cap restricted to featured peptides, and that trigram/edit-distance results are guesses. It also explains the ambiguous-status behavior, which is exactly the kind of outcome semantics an agent needs.
Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.