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Chemical Synonyms & Names

science.chem.names
Read-onlyIdempotent

Get all known names, synonyms, CAS numbers, and registry IDs for a chemical compound. Input any identifier (name, CAS, SMILES, InChIKey) and get the full list of aliases. Useful for finding alternative names, trade names, and cross-references (NCI CACTUS)

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
limitNoMaximum number of names/synonyms to return (1-100). Default: 20
identifierYesChemical identifier to look up synonyms for — compound name, CAS number, SMILES, or InChIKey (e.g. "aspirin", "50-78-2")

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
errorNoPresent only when the call failed. Includes error code, message, request_id, and any provider-specific extras.
resultNoTool response payload. Shape varies per tool — consult the tool description and inputSchema. May be an object, array, string, or number depending on the upstream provider response.

Schema Changelog

Changes observed during successful MCP inspections.

  1. First observed

TDQS

A3.9/5.0
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already indicate a safe, read-only operation. The description adds the source (NCI CACTUS) but no additional behavioral traits beyond what's in the annotations.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is two sentences, front-loaded with the core function, and includes a helpful note on use cases. Every sentence earns its place.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

For a simple lookup tool with rich annotations and an output schema, the description provides sufficient context to understand what it does and how to use it.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema coverage is 100%, so parameters are already well-described. The description adds value by listing supported identifier types and the nature of results, but does not substantially augment the schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the tool returns all known names, synonyms, CAS numbers, and registry IDs for a chemical compound. It specifies the input type (any identifier) and distinguishes its function from sibling tools like synonyms resolvers.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description implies usage for finding alternative names and cross-references, but does not explicitly state when not to use it or contrast with related tools like chemistry.pubchem.synonyms.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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