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Search Biomedical Literature

europepmc.literature.search
Read-onlyIdempotent

Search the Europe PubMed Central (Europe PMC) database of 42M+ biomedical articles, preprints, books, and patents from PubMed/MEDLINE, PubMed Central, and bioRxiv/medRxiv. Supports rich query syntax: free-text terms, field-specific filters (TITLE:"breast cancer", AUTH:"Smith J", JOURNAL:"Nature", DISEASE:"diabetes", MH:"neoplasms" for MeSH, GRANT_AGENCY:"Wellcome Trust", OPEN_ACCESS:Y), and Boolean operators (AND, OR, NOT). Sort by relevance, date, or citation count. Returns article metadata including PMID, DOI, title, authors, journal, year, abstract (with result_type=core), open-access status, and citation count.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
pageNoPage number for pagination (default 1).
sortNoSort order for results. "RELEVANCE" (default) ranks by relevance score. "DATE" returns newest first. "CITED" returns most-cited first.
queryYesEurope PMC search query. Supports full-text search and field-specific syntax: TITLE:"breast cancer", AUTH:"Smith J", JOURNAL:"Nature", DISEASE:"diabetes", MH:"neoplasms" (MeSH), GRANT_AGENCY:"Wellcome Trust", OPEN_ACCESS:Y. Free-text queries search across title, abstract, and MeSH terms.
page_sizeNoNumber of results to return per page (1–100, default 10).
result_typeNoDetail level of results. "lite" returns basic bibliographic fields (title, authors, journal, year, DOI, PMID). "core" adds abstract, keywords, MeSH terms, affiliation, and citation count. Default: "lite".

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
errorNoPresent only when the call failed. Includes error code, message, request_id, and any provider-specific extras.
resultNoTool response payload. Shape varies per tool — consult the tool description and inputSchema. May be an object, array, string, or number depending on the upstream provider response.

Schema Changelog

Changes observed during successful MCP inspections.

  1. Added
  2. Removed
  3. First observed

TDQS

A4.1/5.0
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnly, openWorld, idempotent, and non-destructive behavior, so the description does not need to repeat these. It adds useful behavioral details such as the query syntax support, sorting options, and that result_type=core includes abstract and citation count, which goes beyond the annotations without contradicting them.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is thorough but not bloated; every sentence conveys relevant information about scope, syntax, sorting, and output. It opens with a clear purpose and efficiently packs in details without redundancy. Slightly long, but justified by the tool's complexity.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With an output schema present, the description is not required to list return fields, yet it does, which is helpful. It covers query syntax, sorting, pagination via schema, and result_type distinctions. It lacks explicit mention of rate limits or authentication, but for a read-only search tool these are not critical gaps.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

The input schema has 100% coverage with detailed descriptions for each parameter, including the query syntax examples and valid enums. The description repeats much of this information but does not add new meaning beyond what the schema provides, so the baseline of 3 is appropriate.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the tool searches the Europe PMC database, lists the source databases (PubMed/MEDLINE, PubMed Central, bioRxiv/medRxiv), and describes the return fields. It is distinct from the sibling tools europepmc.literature.article, citations, and references, which target specific retrieval tasks rather than broad search.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description clearly frames the tool as a search interface with rich query syntax and sorting options, giving strong context for its use. However, it does not explicitly mention alternatives (e.g., europepmc.literature.article for fetching a known PMID) or state when not to use it, so it falls short of the highest bar.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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