Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?
Annotations (readOnlyHint=true, destructiveHint=false, idempotentHint=true) already indicate safety. The description adds useful context: 'Returns up to 50 synonyms from a database of millions of name variants (PubChem / NCBI)', which clarifies the result limit and source. No contradiction with annotations.
Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.