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CovaSyn Chemistry Tools

covauv_dissolution

Calculate dissolution profile from UV-Vis absorbance time series.

concentration_unit is REQUIRED and must match the unit the calibration
curve was built in: "mg/mL", "mg/L" or "ug/mL" (the latter two are
equivalent). Dissolution calibrations are most often built in ug/mL — a
100 mg tablet in 900 mL is ~111 ug/mL at full release. Getting this wrong
shifts every result by a factor of 1000, so there is deliberately no
default; the response echoes the unit back and flags implausible profiles
in unit_check.

Optionally calculates f2 similarity if reference_profile is provided.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
api_keyNo
volume_mlNo
timepointsYes
absorbancesYes
label_claim_mgYes
calibration_slopeYes
reference_profileNo
concentration_unitYes
calibration_interceptYes

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
resultYes

Schema Changelog

Changes observed during successful MCP inspections.

  1. First observed

TDQS

Score is being calculated.

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