covabio_viscosity
Estimate viscosity of a protein solution at high concentration. Uses sequence-based heuristic model (Sharma 2014) considering charge, hydrophobicity, and molecular weight. Critical for antibody formulation development.
Parameters:
sequence: Protein amino acid sequence.
concentration_mg_ml: Protein concentration (default 150 mg/mL for subcutaneous).
ph: Formulation pH (default 6.0).
Returns: {viscosity_cP, risk_level, contributing_factors}Input Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| ph | No | ||
| api_key | No | ||
| sequence | Yes | ||
| concentration_mg_ml | No |
Output Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| result | Yes |