covabio_sirna
Design siRNA candidates against a target mRNA sequence using Reynolds 2004 rules. Scores 19-mer windows for efficacy, GC content, thermodynamic asymmetry, and off-target risk. Returns ranked candidate list.
Parameters:
target_sequence: Target mRNA sequence (DNA, minimum 21 nt).
Returns: {n_candidates, candidates: [{position, sense, antisense, score, gc_content}]}Input Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| api_key | No | ||
| target_sequence | Yes |
Output Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| result | Yes |