Locate asparagine deamidation hotspots in a protein sequence — the single most cited chemical-degradation CQA for antibodies and fusion proteins. Scans for the six Asn-Xaa motifs ordered by known lability: NG (critical), NS (high), NH and ND (medium), NA and NT (low). Use to justify a deamidation-monitoring strategy, to compare candidate sequences before lead selection, or to explain a charge-variant shift observed on IEX/icIEF.

This is a sequence-motif rule set, not a structural or kinetic prediction: solvent exposure, local flexibility, pH and temperature all modulate the real rate, and a buried NG can be stable while an exposed ND is not. Treat the output as a site list to test, not a rate.

Parameters:
  sequence: Protein amino acid sequence (1-letter code).

Returns: {deamidation_sites: [{position, motif, risk, context}]} sorted by position