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CovaSyn Chemistry Tools

covabio_cleavage_sites

Map protease cleavage sites and score proteolytic stability. Covers trypsin (after K/R, not before P), chymotrypsin (after F/W/Y, not before P), pepsin (after F/L) and elastase (after A/G/S/V). Returns per-protease position lists, a total site count, a 0-100 stability score and a classification (highly_stable / moderate / proteolytically_labile).

Two uses: predicting in-vivo half-life and serum stability for a peptide therapeutic, and planning the digest for a peptide-mapping or MAM method — the trypsin list is the peptide map you will get.

Returns the same protease analysis that covabio_peptide embeds, on its own and for any protein length.

Parameters:
  sequence: Amino acid sequence.

Returns: {sites: {trypsin, chymotrypsin, pepsin, elastase}, total_cleavage_sites, stability_score, classification}

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
api_keyNo
sequenceYes

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
resultYes

Schema Changelog

Changes observed during successful MCP inspections.

  1. First observed

TDQS

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