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CovaSyn Chemistry Tools

covabio_adc

Design an antibody-drug conjugate (ADC): estimate DAR (drug-to-antibody ratio), total molecular weight, conjugatable cysteine/lysine sites, aggregation risk, and payload hydrophobicity impact.

Parameters:
  antibody_sequence: Antibody amino acid sequence.
  payload_smiles: Drug payload SMILES (e.g. MMAE, DM1).
  target_dar: Target drug-to-antibody ratio (default 4.0).

Returns: {total_mw, dar, conjugation_sites, aggregation_risk, payload_properties}

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
api_keyNo
target_darNo
payload_smilesYes
antibody_sequenceYes

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
resultYes

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